Divine Aleru, Microbiome Signatures Research Coordinator

This review explores the dual role of the intratumoral microbiome in cancer, highlighting its impact on immune modulation and its potential as a target for innovative therapeutic strategies, including enhancing immunotherapy efficacy.

This review explores bacteria-based immunotherapy for cancer, highlighting how bacteria and their components modulate immune responses to enhance tumor targeting and therapy outcomes. It also discusses the potential for combining bacteria with traditional therapies like chemotherapy and immune checkpoint inhibitors.

This review explores the complex role of intratumoral microbiota in cancer, emphasizing their influence on immune responses and the potential for microbiome-based therapies in cancer immunotherapy. It discusses how specific microbes affect tumor progression and therapy resistance, offering insights into new treatment strategies.

This review explores the role of metabolism in cancer, highlighting how tumors adapt their metabolism to survive in the tumor microenvironment (TME) and how systemic metabolism influences treatment. It discusses metabolic reprogramming, immune competition, and the potential for targeted therapies to improve cancer treatment outcomes.

This review explores the complex relationship between inflammation and cancer, examining how chronic inflammation drives tumor initiation, progression, and metastasis. It highlights potential therapeutic strategies targeting inflammatory pathways to improve cancer treatment outcomes.

This review examines the role of intratumoral microbiota in cancer progression, immune modulation, and therapy resistance. It highlights microbial species involved in tumor growth and discusses the potential of microbiome-based treatments to improve cancer therapies.

This review investigates the spatial heterogeneity of intratumoral microbiota and its impact on cancer immunotherapy resistance. It highlights how microbial distribution within tumors influences immune responses and treatment efficacy, suggesting new strategies to overcome resistance and improve cancer therapy outcomes.

The review highlights the role of intratumoral microbiota in cancer initiation, progression, and therapy. It discusses the dual effects of these microbiota on immune responses, emphasizing their potential as diagnostic biomarkers and therapeutic targets in cancer treatment.

This review article explores the role of intratumoral microbiota in cancer initiation, progression, and therapeutic responses. It highlights the complex interactions between microbial communities and the tumor microenvironment (TME) in various cancers, including colorectal, breast, pancreatic, and lung cancers. The review investigates how the presence of specific microbes within tumor tissues influences […]

This review explores the role of fungi in cancer progression, highlighting their impact on tumor development and immune responses. It emphasizes the potential for mycobiome-based cancer diagnostics and therapies, though challenges remain in understanding the exact mechanisms at play.

This review examines the role of intratumoral microbiota in colorectal cancer. It highlights how specific microbes influence tumor progression, immune responses, and therapy resistance, suggesting microbiota manipulation as a novel therapeutic approach.

This review explores how the oral microbiota influences cancer pathogenesis, highlighting its role in immune modulation, inflammation, and tumor progression. It emphasizes the potential of oral microbiota manipulation in improving cancer diagnosis and treatment outcomes.

This review explores how intratumoral microbiota influence cancer initiation, progression, and therapy. It highlights their roles in immune modulation, tumor growth, and therapeutic resistance, suggesting microbiome manipulation as a potential therapeutic strategy.

This review discusses how intratumoral microbiota influence cancer progression and therapy. It explores their roles in immune modulation, inflammation, and treatment resistance, and suggests microbiota manipulation as a potential therapeutic strategy for enhancing cancer treatment outcomes.

This review explores the role of intratumoral microbiota in cancer progression and immunity. It discusses how microbiota influence tumor behavior and therapy outcomes, suggesting potential therapeutic strategies and biomarkers for cancer treatment.

This review explores the role of intratumoral microbiota in cancer onset and progression, emphasizing their potential therapeutic applications in improving cancer treatment outcomes and offering new insights into cancer therapy.

Menarche marks the first occurrence of menstruation, signaling a pivotal moment in a young girl’s transition to womanhood. Understanding this process helps to shed light on the hormonal, physical, and emotional changes that accompany puberty. Explore the importance of menarche, factors that influence its timing, and how it shapes women’s health throughout their lives.

This review elucidates the hormonal and physiological mechanisms underpinning female puberty, detailing HPG and HPA axis activation, pubertal milestones, and regulatory factors, and discusses implications for clinical assessment and future microbiome research integration.

This study identifies significant differences in age of menarche between rural and urban Nigerian girls, highlighting the influence of socioeconomic status and residence. Findings have implications for understanding pubertal timing and its potential links to the microbiome and long-term health risks.

A comprehensive review of evidence on the determinants and health implications of ages at menarche and menopause, highlighting their complex, independent origins and the influence of life-course genetic, environmental, and socioeconomic factors. No consistent direct association was found between the timing of menarche and menopause.

This commentary reviews the global neglect of menstrual health education at menarche, highlighting psychosocial and health consequences for girls. It advocates for standardized, early education and support to empower girls and improve reproductive health, with implications for microbiome-related outcomes.

This study explores the factors influencing age at menarche, menstrual knowledge, and hygiene practices among schoolgirls in Sharjah, UAE. It highlights how socioeconomic factors, education, and hygiene practices impact menstrual health outcomes.

This review explores the link between endometriosis and ovarian cancer, focusing on genetic mutations like ARID1A, oxidative stress, and estrogen receptor loss, which contribute to the development of malignancy, particularly in the endometrioid and clear-cell subtypes.

This review explores the molecular pathogenesis of endometriosis-associated ovarian cancer, highlighting key genetic mutations, hormonal imbalances, and microRNA dysregulation that contribute to the disease. It discusses the potential for personalized treatment strategies based on molecular signatures to improve outcomes in affected patients.