Cadmium Toxicity and Health Effects—A Brief Summary Original paper
Researched by:
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Divine Aleru
ID
Divine Aleru
Read MoreI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.
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Metals
Metals
Heavy metals play a significant and multifaceted role in the pathogenicity of microbial species.
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Divine Aleru
Read More
Researched by:
-
Divine Aleru
ID
Divine Aleru
Read More
Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.
Divine Aleru
What was studied?
The study focuses on cadmium (Cd), a toxic metal that can accumulate in the human body and cause various health issues. It examines how Cd exposure occurs, primarily through inhalation and ingestion, and the subsequent toxic effects it has on the body. The review explores the role of cadmium in chronic diseases, including lung diseases, kidney damage, bone demineralization, and neurological disorders, and it highlights how the metal accumulates over time, especially in high-risk populations like smokers and workers in the metal industry.
Who was studied?
The review addresses the human population exposed to cadmium, particularly those at higher risk, such as workers in the metallurgical industry and individuals who smoke. It also focuses on the general population, discussing exposure through environmental sources like contaminated food and air. The paper highlights how cadmium accumulates in various tissues, especially the lungs, kidneys, and bones, and emphasizes the need for continuous monitoring of at-risk individuals.
Most important findings
Cadmium is primarily absorbed through the respiratory and digestive systems, with 13–19% absorbed via inhalation and 10–44% through ingestion. The accumulation of cadmium in human tissues, particularly the kidneys, lungs, and bones, can lead to long-term health problems. Its biological half-life ranges from 16 to 30 years, meaning it can remain in the body for decades. Chronic exposure to cadmium is linked to a wide range of health issues, including lung diseases, kidney damage, osteoporosis, cardiovascular problems, and neurological disorders. Exposure to cadmium also plays a role in cancer development, particularly lung, prostate, and breast cancer, through mechanisms like oxidative stress and DNA damage.
Key implications
The findings underscore the importance of continuous monitoring for individuals exposed to cadmium, especially those in high-risk groups. Chronic exposure, even at low levels, can cause significant health problems, and the study calls for improved preventive measures, such as stricter occupational safety regulations and dietary interventions. It also stresses the importance of reducing cadmium exposure through public health initiatives and environmental policies aimed at controlling pollution from industrial activities.